Does amniotic fluid puncture hurt?

Amniocentesis is a prenatal diagnosis method, the main purpose is to understand whether the fetus has chromosome abnormalities. Amniocentesis chromosome karyotype analysis is the only gold standard for the diagnosis of fetal chromosome abnormalities at this stage, and there is no other detection method that can completely replace amniotic fluid puncture chromosome karyotype analysis. For Down's screening, 16-18 weeks of Down's screening high-risk population, or maternal peripheral blood fetal DNA testing, that is, non-invasive DNA high-risk population, it is recommended to take amniotic fluid puncture chromosome karyotype analysis. Amniocentesis can be done with local anesthesia, generally not too painful, but amniotic fluid puncture is a traumatic test, may increase the risk of abortion, bleeding, infection. Amniocentesis should be performed only if there are no contraindications to ovine penetration and no symptoms such as acute infection, bleeding, abdominal pain, fever, etc.