Medications for treating uterine fibroids

Gonadotropin-releasing hormone analogues inhibit the secretion of pituitary gonadotropins and reduce estrogen levels in the body, thus reducing the volume of uterine fibroids. These drugs can quickly and effectively relieve symptoms, especially for patients with large fibroids and anemia caused by menorrhagia. They can be applied preoperatively to improve anemia and create better conditions for surgery. However, their disadvantages are that long-term use may lead to climacteric symptoms such as hot flashes, night sweats, etc., and fibroids may grow again after discontinuation. 2. Mifepristone has anti-progesterone and anti-glucocorticoid effects. It can inhibit the growth of uterine fibroids by blocking progesterone receptors. To a certain extent, it can control myoma-related symptoms, such as reduced menstrual flow. However, long-term use may also bring some adverse reactions, such as endometrial hyperplasia, which requires close monitoring during use. At the same time, its long-term effect on fibroids is not very accurate. It should be noted that drug treatment of uterine fibroids is usually suitable for mild symptoms, unsuitable for surgery or patients temporarily unwilling to surgery. Drug treatment does not completely eliminate fibroids, but only plays a certain role in control and remission. When choosing drug treatment, factors such as patient's age, symptoms, fertility needs and characteristics of fibroids should be comprehensively considered, and standardized treatment should be carried out under the guidance of doctors.

Regular follow-up is also needed to monitor changes in fibroids and the effectiveness of medications. If medications do not work well or fibroids continue to grow, other treatments such as surgery may be considered.