How to determine neurosyphilis

Neurosyphilis belongs to tertiary syphilis. The incidence of neurosyphilis is about 10%, and it usually occurs after 3 to 20 years of infection. The main types are asymptomatic neurosyphilis, tuberculosis, paralytic dementia, cerebral (spinal cord) membranous neurosyphilis, etc. The diagnosis of neurosyphilis should be carefully inquired about the history, clinical manifestations and laboratory tests. Laboratory tests for syphilis include nonspecific antibody tests for syphilis, specific antibody tests for syphilis, and examination of the patient's cerebrospinal fluid. Examination of brain effusions for neurosyphilis may show elevated white blood cells, elevated protein levels, and positive VDRL tests. CT and MRI examinations may also be performed. In addition, it should be differentiated from other central nervous system diseases or psychiatric disorders.