Symptoms of neurosyphilis

The main clinical manifestation of neurosyphilis is "tabes dorsalis", which usually occurs 20 to 30 years, or 5 to 50 years after infection. The affected site is the posterior column and root of the spinal cord, resulting in progressive ataxia with progressive loss of peripheral nerve reflexes and vibration sensation disorders. Typical triad symptoms include lightning-like pain, sensory disturbance, and urinary retention. The most common and earliest triad symptoms are pupil abnormalities, loss of lower limb reflexes, and Umber's sign. Spinal tuberculosis is also often accompanied by optic atrophy. Paralytic dementia, onset 3 to 20 years after infection. It is encephalomyelitis caused by direct invasion of the brain by Spirochaeta pallida, resulting in progressive cortical dysfunction. The greatest damage is to mental intelligence. There is extensive brain damage, including personality, emotion, reflexes, hyperreflexia, eye, sensory center (illusion, delusion, hallucination, mental and language ability abnormalities.