sperm DNA fragmentation

Sperm DNA fragmentation refers to the damage of sperm DNA integrity caused by harmful factors during sperm formation.

Sperm DNA fragmentation, also known as sperm DNA fragmentation or damage, refers to the damage of sperm DNA integrity caused by adverse factors during sperm formation (such as oxidative stress, smoking, high temperature, drugs, radiation and chemotherapy, environmental toxins, etc.), and then breaks into single-stranded DNA fragments. This fragmentation reflects the integrity of sperm genetic material and is closely related to male fertility.

Sperm DNA fragmentation rate (DFI) refers to the proportion of sperm DNA fragments broken into single-stranded DNA. Generally speaking, DFI≤15% indicates that sperm DNA integrity is good;15%