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Urticaria is the most likely cause of systemic allergies. Urticaria treatment should first actively seek and prevent suspicious allergens, common allergens are animal protein, food additives and other food factors, dust mites, pollen, animal dander and other inhalation factors, as well as drugs, infection factors. If the lesion area is not very large and there are no systemic symptoms such as dyspnea, throat foreign body sensation, diarrhea, abdominal pain, etc., it is recommended to take oral antihistamines such as ebastine tablets and loratadine tablets. Topical application of calamine lotion or hydrocortisone butyrate cream is also recommended. If the patient is seriously ill, it is recommended to go to the hospital and be given the corresponding treatment plan by the doctor according to the specific situation.