Causes of sperm chromosome abnormalities
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Sperm chromosome abnormalities are caused by environmental factors, genetic factors and drug factors.
1. Environmental factors
Long-term exposure to ionizing radiation, alkylating agents, nitrosamines and other substances may induce sperm chromosome abnormalities.
2. Genetic factors
If a relative has sperm chromosome abnormalities, the individual's susceptibility may increase, resulting in the performance of sperm chromosome abnormalities. This abnormality is an inherent genetic programming mode of the human body, so it cannot be regulated.
3. Drug factors
Long-term use of certain drugs, such as thymosin enteric-coated tablets, transfer factor oral solution and other immune modulators, or hypertension drugs, cytotoxic drugs, etc., may affect sperm DNA replication and synthesis, resulting in chromosome abnormalities and abnormal morphology.
Sperm chromosome abnormalities may lead to decreased fertility, increased risk of abortion and premature birth, and increased risk of genetic diseases. This abnormality may adversely affect the health of men and offspring by affecting sperm quality, quantity and transmission of genetic information.
