Langerhans cell histiocytosis is what happens.

Langerhans cell histiocytosis is caused by gene mutation in most cases. Smoking, perinatal infection and other factors may induce Langerhans cell histiocytosis.

1.

Gene mutation in MAPK pathway in patients can activate Langerhans cells in their bodies, promote Langerhans cell growth and reproduction, and trigger Langerhans cell histiocytosis

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2

. Perinatal infection When pregnant

women are infected with pathogens in perinatal period, it can cause abnormal fetal immune function in their bodies, resulting in abnormal cell proliferation. Patients can develop Langerhans cell histiocytosis.