How does thrombocytopenia come about?

Thrombocytopenia may be caused by a variety of factors

. Thrombocytopenia or ineffective death is one of the main causes, which may include both genetic and acquired conditions. Acquired thrombocytopenia may be caused by factors such as drugs, malignant tumors, infections, ionizing radiation, etc. that damage hematopoietic stem cells or affect their proliferation in bone marrow. In addition, excessive platelet destruction is also an important cause, including congenital and acquired types. Excessive acquired platelet destruction may be caused by autoimmune and non-immune factors. Common diseases include idiopathic thrombocytopenic purpura and thrombotic thrombocytopenic purpura. Finally, excessive platelet retention in the spleen may also lead to Thrombocytopenia, most commonly seen in hypersplenism.