How to lose weight with metformin

Metformin is an oral hypoglycemic agent commonly used in diabetic patients, belonging to the first-line hypoglycemic drugs. The hypoglycemic mechanism of metformin is mainly to inhibit the output of liver glycogen and increase the sensitivity of peripheral tissues, especially muscle tissues, to insulin. The main side effects of metformin are gastrointestinal reactions, such as nausea, vomiting, diarrhea, some patients can show the taste of metal in the mouth, obese diabetes patients and simple obesity patients, it is the use of the side effects of metformin into a positive effect, both to reduce blood sugar, but also weight loss, so type 2 diabetes and simple obesity patients preferred metformin. It is worth noting that metformin itself has no damage to liver and kidney. When liver and kidney function are abnormal, metformin is not recommended because it can increase the load of liver and kidney function. It is not easy to increase the amount during use, because high doses and long-term use can also cause lactic acidosis, which is another side effect of metformin, but the incidence of side effects is very low.