Causes of high gastrin-releasing peptide precursor

High gastrin-releasing peptide precursors may be caused by diseases such as gastritis, duodenal ulcer, and gastrinoma.

1. Gastritis: Gastritis is caused by Helicobacter pylori infection, alcohol stimulation, trauma, etc. Under the stimulation of inflammation, a large amount of gastric acid is secreted, resulting in high gastrin-releasing peptide precursors.

2. Duodenal ulcer: Duodenal ulcer may be caused by drug factors, invasion of gastric acid and pepsin, etc., and can also cause excessive gastric acid secretion, resulting in high gastrin-releasing peptide precursors.

3. Gastrinoma: The etiology of gastrinoma is not yet clear, and may be related to genetic mutations in pancreatic a1 cells, which can lead to high secretion of gastric acid and high gastrin-releasing peptide precursors.