How to diagnose contrast nephropathy

Doctors diagnose contrast-induced nephropathy mainly based on medical history, clinical manifestations, laboratory examinations and imaging examinations.

1. There is a clinical history of contrast medium use.

2. Proteinuria and acute kidney injury occur within 72 hours after the contrast examination.

3. Urine examination: Urine examination shows that renal tubular epithelial cells, red cells, white cells and epithelial cell casts appear in the urine.

4. Renal tubular function test: indicating renal tubular function damage.

5. Glomerular function test: Blood urea nitrogen, serum creatinine, and uric acid can all increase, and endogenous creatinine clearance rate decreases, indicating glomerular function damage.

6. Radionuclide renogram and B-ultrasound examination: The renogram is parabolic; the B-ultrasound renal shadow is enlarged or normal.

7. Renal biopsy: If there are changes such as destruction of the tubular cytoskeleton structure and degeneration and necrosis of epithelial cells, it is helpful for the diagnosis of this disease.