What causes high uric acid in knee joint pain?

High uric acid causes knee joint pain mainly due to urate crystal deposition, inflammatory reaction, joint damage and other factors, need to seek medical attention in time, adjust diet, severe can use drugs to relieve symptoms. High uric acid causes knee joint pain mainly due to the following: 1. Urate crystal deposition: Uric acid is the end product of purine metabolism. When the blood uric acid level is too high, urate crystals can deposit in joints, synovium, cartilage and other parts, resulting in inflammation and pain. 2. Inflammation: urate crystal deposition activates inflammation and releases inflammatory mediators, such as interleukin-1, tumor necrosis factor-α, etc., causing joint redness, pain, fever and other symptoms. 3. Joint injury: High uric acid may also lead to articular cartilage damage, synovial hyperplasia, etc., which may cause knee pain. 4. Other factors: genetic factors, dietary factors, obesity, hypertension, diabetes, etc. may also increase the risk of knee joint pain caused by high uric acid. In addition, for knee joint pain caused by high uric acid, it is necessary to seek medical attention in time for relevant examination and treatment. At the same time, patients should pay attention to diet adjustment, reduce the intake of high-purine foods, such as animal viscera, seafood, beer, etc., drink plenty of water, promote uric acid excretion. If the pain is serious, you can use drugs to relieve symptoms under the guidance of a doctor. In short, the causes of knee joint pain caused by high uric acid are complex, and multiple factors need to be considered comprehensively. Patients should seek medical attention in time, take corresponding treatment measures, and pay attention to diet and lifestyle adjustment to alleviate symptoms and prevent complications.