How to treat white matter disease

White matter is an important part of the central nervous system, where nerve fibers gather. Damage to the myelin sheath of central nerve cells in white matter can cause white matter lesions. Symptoms and signs of the nervous system vary, depending on the site and extent of the lesion. Clinically, visual, motor, sensory, cerebellar, autonomic and cognitive dysfunction are visible. The etiology of white matter disease is complex and diverse, broadly divided into acquired demyelination and hereditary demyelination disorders, such as multiple sclerosis, acute disseminated encephalomyelitis, optic neuritis, encephalitis, etc. These demyelination diseases can be treated with high-dose hormone pulse therapy and gamma globulin and plasma exchange therapy. For inherited myelination disorders, such as adrenoleukodystrophy, treatment methods are relatively limited, generally bone marrow transplantation, or symptomatic treatment for the symptoms of the disease.