What is lupus encephalopathy?

It is a manifestation of neuropsychiatric symptoms of systemic lupus erythematosus, and one of the main causes of death in lupus crisis. Its clinical manifestations mainly include: first, epilepsy, epilepsy can occur in the early stage, even before the current skin symptoms, late stage can be seen more frequently, can be manifested as systemic seizures and partial seizures, can show status epilepticus, and even lead to death. Second, mental symptoms and cognitive impairment, manifested as emotional instability, easy to excite, anxiety, depression and other emotional changes, auditory, visual hallucinations and delusions, psychomotor excitement and other mental symptoms, disorientation, inattention, slow thinking, memory decline, etc., a small number of patients with severe dementia, hormone treatment patients with higher incidence of mental symptoms. Third, myelitis is rare and often occurs during the active period of the disease. It is spinal cord vasculitis that leads to spinal cord ischemia, necrosis, softening and subacute spinal cord white matter degeneration. Spinal cord damage is often located in the thoracic segment and is manifested as weakness of both lower limbs., loss or disappearance of sensation below the damaged plane, dysfunction of urination and defecation, poor prognosis of chronic myelitis, and often death due to secondary infection. Four, stroke, systemic lupus erythematosus caused vasculitis can lead to vascular occlusion, rupture bleeding, and systemic lupus associated with hypertension, uremia increased the possibility of cerebral vascular occlusion or bleeding. Five, brain stem damage, manifested as tinnitus, vertigo, but also can show related cranial nerve damage, such as oculomotor, facial nerve, glossopharyngeal, hypoglossal nerve and so on more common cranial nerve. Six, aseptic meningitis. Seven, peripheral neuropathy. Eight, muscle damage performance for muscle pain weakness and other performance. Nine, dance-like movements, adolescents more common.