What causes white matter degeneration?

The first reason is cerebral ischemia, if the patient has hypertension, causing deep arterioles to show hyaline change, showing arterial occlusion, white matter will show ischemia, hypoxia necrosis, thus causing white matter degeneration; The second reason should pay attention to demyelinating diseases of the central nervous system, such as multiple sclerosis, optic neuromylitis, because of the existence of immune function disorders, causing white matter damage, showing white matter degeneration; In the third case, attention should be paid to whether there is poisoning, such as alcoholism, carbon monoxide poisoning, etc., which can also cause white matter to show lesions; in addition, if vitamin B12 shows deficiency, it can also cause degeneration of white matter.