What causes a few white matter demyelination changes?

A few demyelination changes in the brain, the most common reason is due to cerebral white matter ischemia, hypoxia, but also may be due to the central nervous system autoimmune demyelination disease, infection poisoning, nervous system degenerative diseases secondary performance, generally do head magnetic resonance imaging is the most clear. The common ischemic and hypoxic diseases with demyelinating changes in white matter are subcortical arteriosclerosis encephalopathy, and the common autoimmune demyelination diseases, multiple sclerosis progressive multifocal leukoencephalopathy, acute disseminated encephalomyelitis, central pontine myelinolysis, etc.