How to diagnose autoimmune hemolytic anemia during pregnancy
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The diagnosis of pregnancy complicated with autoimmune hemolytic anemia mainly depends on clinical manifestations, laboratory tests, including blood routine test, anti-human globulin test, other autoantibodies test, bone marrow image, etc., and is diagnosed after comprehensive judgment.
According to the clinical characteristics of pregnancy complicated with autoimmune hemolytic anemia, the diagnosis is mainly made through the following tests
: High reticulocyte count, low hemoglobin, mainly microcytic hypochromic anemia.
Antiglobulin test: direct antiglobulin test positive, suggesting red blood cells sensitized by autoantibodies.
Other tests: indirect antiglobulin test, Coombs test, cold agglutinin test, etc. may also assist in diagnosis.
Other autoantibody tests: Such as anti-nuclear antibodies, anti-double-stranded DNA antibodies, etc., help to determine whether there is autoimmune disease.
Bone marrow: bone marrow hyperplasia active, mainly erythroblasts.
Other tests: liver function, kidney function, thyroid function and other tests to rule out other possible causes of anemia. To sum up, the diagnosis of pregnancy
with autoimmune hemolytic anemia mainly depends on clinical manifestations, laboratory tests and other comprehensive judgment. After diagnosis, active treatment should be taken to ensure the safety of mothers and infants.
