mitochondrial encephalopathy

Mitochondria is an important and unique organelle in human eukaryotic cells. It is called intracellular power plant and provides energy for various life activities of cells. Mitochondrial encephalopathy is rarely manifested alone. It is usually combined with mitochondrial myopathy, so it is clinically called mitochondrial encephalomyopathy. Mitochondrial encephalopathy is a group of rare mitochondrial structural or functional abnormalities caused by brain and muscle involvement. Muscular impairment is characterized by skeletal muscle intolerance and inability to tolerate fatigue. Neurological manifestations include extraocular muscle paralysis, stroke-like seizures, recurrent seizures, myoclonus, migraine, ataxia, mental retardation, and optic neuropathy. Other systems may be characterized by cardiac conduction block, cardiomyopathy, diabetes, renal insufficiency, pseudoileus, and short stature.