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Contraceptives can regulate menstruation. The commonly used contraceptives are hormonal contraception methods. The hormonal components of contraceptives are mainly estrogen and progesterone. In a menstrual cycle, estrogen accounts for the main role in the first two weeks. The secretion of progesterone increases in the last two weeks of the menstrual cycle. Under the joint action of estrogen, the endometrium presents a change in secretion period, which is conducive to the colonization of fertilized eggs in the endometrium. Before menstruation comes, estrogen and progesterone levels in the body suddenly decrease, and the functional layer of the endometrium lacks hormone stimulation and necrosis, that is, menstrual cramps. Oral contraceptives can change estrogen and progesterone levels in the body, artificially control menstrual cycles, and regulate irregular menstrual cycles.