blocking antibody negative fetal arrest relationship

Negative blocking antibodies can cause fetal arrest. In the serum of normal pregnant women, there is a specific antibody against partner lymphocytes, which can inhibit lymphocyte reaction, block the cytotoxic effect of maternal lymphocytes on cultured trophoblast, prevent the auxiliary t cells from recognizing fetal antibodies, prevent the mother's immune system from attacking the embryo, block the lymphocytes stimulated by alloantigen to produce macrophages, and move the inhibitor, which is called blocking antibody. The most direct understanding is that blocking antibody is a good thing, it can play a certain protective role and positive role, especially for pregnant women. Normal blocking antibody can be detected, but if frequent abortion or other reasons, it may not detect this kind of thing, need to actively deal with, check its significance is to predict the effect of pregnancy and childbirth to a certain extent, positive is good negative is not very good.