Does chemo get worse each time?

Whether chemotherapy is more uncomfortable each time is affected by many factors, including the patient's physical condition, chemotherapy regimen adjustment, patient's psychological state, side effect management, etc. 1. The patient's physical condition If the patient's physical condition is good before chemotherapy, nutrition is adequate, and organ function is normal, then the tolerance to chemotherapy may be relatively good, and it may not feel more uncomfortable each time. On the other hand, if the patient has some underlying disease or is weak, subsequent chemotherapy may bring more obvious discomfort. 2. Chemotherapy regimen adjustment The doctor will adjust the chemotherapy regimen according to the patient's response after each chemotherapy and the change of the disease. Reasonable adjustment may reduce the side effects so that the patient does not feel more uncomfortable each time. For example, reduce the dose of drugs, change the type of drugs or adjust the order of medication, etc. 3. Positive and optimistic mental state of patients helps patients better cope with the discomfort caused by chemotherapy. If the patient has been in anxiety, fear, may amplify the body discomfort, on the contrary, maintain a good state of mind, with appropriate psychological counseling, may make the patient subjectively feel less uncomfortable. 4. Side effect management Medical staff through early antiemetics, organ function protection drugs and other measures, can reduce the side effects of chemotherapy to a certain extent. Patients themselves can also strengthen their physique and improve their tolerance to chemotherapy through reasonable diet and moderate exercise. Patients and medical staff should work closely together to minimize the discomfort caused by chemotherapy and improve the treatment effect.