Azacitidine is chemotherapy?

Azacitidine is a chemotherapeutic agent.

Azacitidine exerts its antitumor effect by inhibiting DNA methylation, thereby affecting gene expression and proliferation of tumor cells. It can reactivate tumor suppressor genes silenced by abnormal methylation and induce differentiation and apoptosis of tumor cells. It is mainly used to treat hematological malignancies such as myelodysplastic syndrome. Azacitidine has been shown to improve hematological parameters and delay disease progression in these diseases.

Azacitidine has shown some efficacy in appropriate patient populations, improving response rates and prolonging survival. However, the efficacy varies with individual patients.

Azacitidine may cause some adverse reactions, such as bone marrow suppression, gastrointestinal discomfort, fatigue, etc. Azacitidine,

as a chemotherapeutic agent, plays an important role in the treatment of hematological malignancies. However, its use needs to be carried out under the guidance of professional doctors, strict indications and contraindications, and individualized treatment and monitoring according to the specific conditions of patients to ensure the safety and effectiveness of treatment.