Diagnostic criteria for hepatitis B virus-associated nephritis

According to the diagnostic criteria for hepatitis B virus-associated nephritis, the following is a serious medical original compilation of diagnostic criteria for hepatitis B virus-associated nephritis.(HBV-GN) is a glomerular disease caused by hepatitis B virus (HBV) infection. The diagnosis requires a combination of clinical symptoms, laboratory tests, evidence of HBV infection, and renal pathology. The following are the diagnostic criteria for hepatitis B virus-associated nephritis: 1. HBV antigen positive: HBsAg positive. Hepatitis B e antigen (HBeAg) positive. Hepatitis B core antibody (Anti-HBc) IgM positive.2.Determination of serum HBVDNA load: HBV DNA load increased.3.Abnormal urine examination: proteinuria: urine protein qualitative positive or 24-hour urine protein quantitative ≥ 0.15g.Hematuria: microscopic hematuria or macroscopic hematuria. 4.Renal pathological examination: Hepatitis B virus antigen deposition in glomerular mesangial area. Or (and) electron dense deposition seen on the epithelial side of glomerular basement membrane. Immunopathological examination shows hepatitis B virus surface antigen or core antigen. 5. Glomerular diseases caused by other reasons: lupus nephritis, allergic purpura nephritis, etc. It should be noted that the following groups need special attention when diagnosing: Children patients: HBV infection is more likely to lead to nephritis, and the renal pathological type is mostly membranous nephropathy. Immunocompromised people: such as AIDS patients, patients receiving immunosuppressant therapy, etc., infected with HBV are prone to nephritis. Family history of hepatitis B: relatives of hepatitis B patients, the risk of HBV-GN is relatively high. For patients suspected of HBV-GN, relevant examinations should be carried out in time, including hepatitis B five items, HBVDNA quantitative, urine examination, renal pathological examination, etc., to confirm the diagnosis. once diagnosed, comprehensive measures such as antiviral therapy and immunosuppressive therapy should be actively taken to protect renal function and delay the progression of the disease. In summary, the diagnosis of hepatitis B virus-associated nephritis requires a combination of factors, early diagnosis and treatment is essential to protect kidney function. If there are related questions, it is recommended to consult a professional nephrologist.