Principles and effects of chemotherapy for pulmonary tuberculosis

The principle of chemotherapy for pulmonary tuberculosis is early, regular, whole process, appropriate and combined. The whole treatment scheme is divided into two stages: intensive stage and consolidation stage. Early stage means that all patients detected and diagnosed should be given chemotherapy immediately. Early chemotherapy is conducive to rapid early sterilization, promoting lesion absorption and reducing infectivity. The rule is to strictly follow the doctor's advice and regularly use drugs without omission and continuous use to prevent the occurrence of drug resistance. The whole process is to ensure the completion of the prescribed treatment period, which is an important measure to improve the cure rate and reduce the recurrence rate; the appropriate amount is to strictly follow the appropriate drug dose, the drug dose is too low to achieve effective blood drug concentration, affecting the efficacy and easy to produce drug resistance, too large a dose is easy to produce drug toxic side effects; combination medication refers to the simultaneous use of multiple anti-tuberculosis drugs, which can improve the efficacy, and at the same time reduce and prevent the occurrence of drug resistance through cross-sterilization. Commonly used anti-tuberculosis drugs are isoniazid, rifampicin, pyrazine amide, ethambutol, for retreatment patients can be added as circumstances such as streptomycin.