Treponema pallidum antibody is positive to explain syphilis?


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Syphilis is a systemic sexually transmitted disease caused by Treponema pallidum infection. After a human body is infected with Treponema pallidum, the immune system will produce various antibodies against the treponema pallidum, which are mainly divided into two categories. One is specific Treponema pallidum antibodies, which are the only ones infected with syphilis. Also called TP antibodies. The other type is non-specific Treponema pallidum antibodies, also called anticardiolipin antibodies or RPR antibodies. Normal Treponema pallidum antibodies usually refer to specific antibodies, and a positive specific antibody indicates a previous infection with syphilis. However, it cannot be determined whether it is a previous infection or a current infection, and whether the disease is in the active stage cannot be determined. Therefore, it is normal to combine another anticardiolipin antibody, that is, non-specific syphilis spirochete antibody, together with comprehensive analysis. If the latter is also positive and has a higher titer, it indicates that the patient is present syphilis and needs active anti-syphilis treatment.