Syphilis hit 3 needle to turn negative immediately

Syphilis is a systemic sexually transmitted disease caused by Treponema pallidum infection. Treponema pallidum is highly sensitive to penicillin. So far, there is no drug resistance phenomenon. Therefore, the normal treatment of syphilis is to use long-acting penicillin intramuscular injection, which is normally once a week for three consecutive injections. After completing the standard treatment course of three weeks normally, the syphilis antibody titer in the blood cannot be immediately negative, so it normally needs to be rechecked once every three months. It normally takes 1-2 years before the patient's RPR titer gradually decreases and turns negative, which indicates that Treponema pallidum is eliminated in the body, and the condition is improved and cured. However, there are also some patients whose titer is fixed at a lower level and will no longer turn negative. At this time, the possibility of neurosyphilis should be ruled out. If necessary, cerebrospinal fluid examination or penicillin treatment should be carried out according to neurosyphilis.