What does syphilis specific antibody negative mean?

Syphilisis-specific antibody negative, that is, in the blood there is no detection of syphilis specific antibodies. After human infection with Treponema pallidum, the body can produce a variety of antibodies, mainly including specific antibodies and non-specific antibodies two types. Among them, specific antibodies are unique to syphilis infection, other diseases do not produce such antibodies. Therefore, if detected in the blood there are such antibodies, you can diagnose syphilis. However, if the syphilis spirochete antibody is negative, there are two possibilities. One is really not infected with syphilis, of course, there is no specific antibody, so it is negative. The other is already infected with syphilis, but because it is in the window period, the blood has not yet had time to produce antibodies, or the antibody produced is not enough to reach the detection standard, so it is still negative. At this time, you can delay 2 to 4 weeks to review again. If it is still negative, you can rule out syphilis.