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What are the causes of ankylosing spondylitis?


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Ankylosing spondylitis is caused by genetic, infection, immune dysfunction, etc.
1, genetic
ankylosing spondylitis and HLA-B27 gene has a certain relationship, one or both parents with ankylosing spondylitis, their children detected HLA-B27 gene positive probability will greatly increase, the risk of disease will also increase accordingly.
2, infection such
as urinary system inflammation, gastrointestinal inflammation, etc., the pathogen can be transferred to the spine and other parts with blood circulation, and then cause stimulation and damage to surrounding tissues, resulting in ankylosing spondylitis.
3, immune dysfunction
Due to alcoholism, inflammatory stimulation, immune diseases and other reasons, leading to immune dysfunction, in the attack of pathogens at the same time, but also kill normal human cells, resulting in ankylosing spondylitis.