Causes of cervical iodine staining

1. Cervical intraepithelial neoplasia When abnormal changes occur in the cervical epithelium, low-grade or high-grade lesions occur, often lead to iodine non-staining. This is because the pathological epithelial cells and normal epithelial cells in the structure and function of differences, affecting the uptake and response to iodine. 2. Inflammatory lesions long-term cervical inflammation stimulation may make the structure and nature of the cervical epithelium change to some extent, in the iodine test may also appear not stained. However, this situation is different from precancerous lesions or cancer caused by non-staining, which needs to be further combined with other examinations to comprehensively judge.3. Operational technical factors If the concentration of iodine solution is inaccurate, the application is not standardized or the observation is not careful, it may also cause false positive or false negative results, affecting the correct judgment of cervical iodine non-staining. 4. Cervical cancer cervical cancer tissue usually lack affinity for iodine, thus presenting iodine non-staining phenomenon. With the proliferation and invasion of cancer cells, the normal structure and function of cervical tissue are destroyed, resulting in this special performance. When it is found that cervical iodine is not stained, the diagnosis cannot be confirmed solely by this result, but comprehensive evaluation and analysis should be carried out in combination with medical history, clinical manifestations, cytological examination, HPV detection and tissue biopsy when necessary to determine the specific cause and take corresponding treatment measures.