How much does hepatitis B surface antibody need to be strengthened?

Hepatitis B surface antibody is a protective antibody that neutralizes hepatitis B virus and prevents infection. In general, the titer of hepatitis B surface antibody decreases over time. When the titer of hepatitis B surface antibody is less than 10 mIU/ml, the risk of hepatitis B virus infection increases, and a booster shot may be required. However, for some special groups, even if the titer of hepatitis B surface antibody is greater than 10 mIU/ml, a booster shot may be required.

For example, people at high risk of hepatitis B virus infection, such as medical personnel, people who frequently come into contact with blood or body fluids, family members of hepatitis B virus carriers, etc.; people with low immune function, such as AIDS patients, patients receiving immunosuppressant treatment, etc. The immune system of these populations may not be able to produce sufficient HBsAg efficiently, so even if HBsAg titers are greater than 10 mIU/ml, a booster dose of HBV vaccine may be required. In addition, for some special circumstances, such as receiving immunoglobulin therapy, long-term use of immunosuppressants, etc., it may also be necessary to decide whether to vaccinate hepatitis B vaccine booster according to specific circumstances. It should be noted that hepatitis B vaccine booster is not required by everyone, and whether to vaccinate should be decided according to individual circumstances. It is recommended to consult a doctor or professional medical institution for detailed consultation and evaluation. In short, hepatitis B surface antibody titer is not the only criterion for judging whether hepatitis B vaccine booster is needed. Individual circumstances should also be considered. If there is any doubt about hepatitis B vaccination, consult a doctor or professional medical institution in time to make the right decision.