Other names for IgA nephropathy

IgA nephropathy is also known as Berger disease.

IgA nephropathy is a glomerular disease characterized by proliferation of mesangial cells, increased stroma, and extensive IgA deposition. Since Berger first described the disease in 1968, IgA nephropathy is also known as Berger disease. The specific pathogenesis of IgA nephropathy is unknown. At present, it is believed that it may be related to heredity and abnormal glycosylation of IgA1 molecule. It is mostly secondary to diseases such as upper respiratory tract infection, intestinal infection and urinary system infection. It is mainly manifested as macroscopic and microscopic hematuria, proteinuria, edema, lumbago and hypertension. If treatment is not timely, it may also cause renal failure of different degrees with the deterioration of the disease.