The fourth chemotherapy is the hardest.

Chemotherapy is the fourth most unpleasant treatment. Chemotherapy is an important treatment for cancer, but it is often accompanied by a series of serious side effects, and the fourth chemotherapy, patients may experience more intense discomfort. First, the physical fatigue will be particularly obvious. After the accumulation of previous chemotherapy, the body's energy consumption is huge. At this time, the patient will feel extremely weak. Daily activities become extremely difficult, as if the whole body's strength has been withdrawn. This fatigue is not only physical, but also mental pressure. Secondly, nausea and vomiting may be more serious. Chemotherapy drugs stimulate the gastrointestinal tract further, resulting in frequent nausea, vomiting may become difficult to control, seriously affecting eating and nutrition intake, making the body weaker. Moreover, bone marrow suppression may lead to significant decreases in white blood cells, red blood cells, platelets and other indicators. This makes the patient more susceptible to infections, anemia, and bleeding, further threatening health and requiring close monitoring and timely intervention. Neurotoxicity may also become more prominent. Patients may experience paresthesia such as numbness and tingling in their hands and feet, and even affect their normal mobility, which causes many inconveniences and disturbances in life. Finally, psychological stress reaches a peak. In the face of extreme physical discomfort and worry about future treatment, patients are prone to anxiety, depression and other adverse emotions, which in turn affect the treatment effect and physical recovery. The fourth discomfort of chemotherapy is multi-faceted, requiring more comprehensive care and support from medical staff, patients themselves also need to maintain strong will, family members should also give full understanding and encouragement, together through this difficult stage.