What drugs are used for gout

Gout patients can follow the doctor's advice to use non-steroidal anti-inflammatory drugs, colchicine, glucocorticoids, uric acid lowering drugs, etc. 1. Non-steroidal anti-inflammatory drugs such as ibuprofen, indomethacin, etc., can effectively relieve the pain and swelling of acute gouty arthritis. These drugs play an anti-inflammatory, analgesic and antipyretic role by inhibiting cyclooxygenase and reducing prostaglandin synthesis. Colchicine is a classic drug for acute gout attacks. It inhibits inflammatory cell chemotaxis and reduces inflammatory factor release, thus quickly relieving joint pain and swelling. However, colchicine may cause gastrointestinal discomfort, diarrhea and other adverse reactions. It should be taken strictly according to the prescribed dosage. 3. Glucocorticoids can be considered for use when acute gout attacks are severe and other drugs are ineffective. It has strong anti-inflammatory effects and can quickly relieve symptoms, but long-term use in large quantities may bring many adverse reactions, such as elevated blood sugar and osteoporosis. 4. Uric acid lowering drugs include allopurinol, febuxostat, benzbromarone, etc. It is indicated for gout patients in intermittent and chronic phases to reduce serum uric acid levels and prevent gout attacks. Allopurinol reduces uric acid production by inhibiting xanthine oxidase; febuxostat acts similarly; benzbromarone acts mainly by promoting uric acid excretion. When using these drugs, attention should be paid to monitoring blood uric acid levels and possible adverse reactions, such as allopurinol may cause allergic reactions, etc. The selection and use of drugs should be carried out under the guidance of doctors according to the specific conditions of patients, such as severity of disease, concomitant diseases, allergic history, etc. At the same time, patients also need to pay attention to adjust lifestyle, such as low purine diet, smoking cessation and alcohol restriction, moderate exercise, weight control, etc., in order to better control gout. In addition, in the use of drugs in the process of close observation of adverse reactions, if abnormal should be treated in time.