What is sigmoid polyps?

Sigmoid colon polyps are usually related to genetic factors, bile metabolism disorders, intestinal inflammatory diseases, etc. The specific analysis is as follows:

1. Genetic factors

If the patient has a family genetic history of sigmoid colon polyps, it is easy to cause APC allelic tumor suppressor gene mutation in the long arm of chromosome 5, resulting in sigmoid colon polyps.

2. Bile metabolism disorders

Because the patient has cholecystectomy, gastrojejunostomy, etc., it is easy to cause bile metabolism disorders, resulting in increased bile acid levels in the large intestine. With tissue metabolism, bile acids will be decomposed into lithocholic acid and deoxycholic acid, which will stimulate intestinal mucosa and cause sigmoid colon polyps.

3. Intestinal inflammatory diseases

Because the patient has Crohn's disease, intestinal tuberculosis, chronic ulcerative colitis, amebic dysentery, etc., it will cause long-term stimulation to intestinal mucosa, causing local tissue lesions, resulting in sigmoid colon polyps.