What about molecular targeted therapy resistance?

A possible solution to the problem of resistance to molecular-targeted therapy is to replace or combine other targeted drugs, or try non-targeted chemotherapy, radiotherapy, immunotherapy, etc.

Molecular-targeted therapy is a treatment that targets specific molecules (e.g., proteins, genes, etc.) and inhibits tumor growth and spread. However, due to the complexity and heterogeneity of tumor cells, some patients may develop resistance to molecular-targeted therapy. This may be due to genetic mutations in tumor cells or other mechanisms that bypass the inhibition of targeted drugs.

When molecular-targeted therapy develops resistance, doctors may recommend genetic testing to understand genetic changes in tumor cells and select new targeted drugs based on this information. In addition, combining multiple targeted drugs or other treatments, such as chemotherapy, radiotherapy, immunotherapy, etc., may also help overcome resistance.